The 56-year-old has been performing tracks from her four-decade career on the current leg of her Tension tour.
At her show at Los Angeles' Crypto.com Arena on Friday, US time, she admitted she was overwhelmed and "very, very grateful".
"Here we are in 2025 and I get to be on a world tour with these beautiful humans, beautiful intelligent humans - the ones you can see on the stage and off stage," she told the audience, according to Billboard.
"And I get very emotional thinking about this, this … it's been a lifetime and sometimes it just amazes me. So very, very grateful. Thank you so much for being here."
And before her final song, Love at First Sight, the Padam Padam hitmaker thanked her fans for their "beautiful energy" and gave a special "shout-out" to all those who had worked on the tour.
"You've been beyond tonight. You've been here, present, ready, going — thank you so much for being here, for your beautiful energy, for being here for me in all different times of my career. For being there for each other!
"I just want to give a real shout-out to our entire crew because this has been an incredible run. We've loved it, so thank you."
Minogue began the Tension tour in Perth, before heading for three dates in Asia in March and on to a 16-date run of shows in Canada and the US.
She will then head to Europe later in May, before taking the concert series to South America on August 7, rounding out the world tour with three shows in Mexico.
By the end of the run, she will have played almost 70 shows in more than 25 countries on five continents.
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