Adelaide star Ebony Marinoff and Brisbane's Ally Anderson will become the first players in the women's competition to play 100 games when they run out in their respective games on Sunday.
The pair, both league best-and-fairest winners, have remarkably never missed a game since the league's inception in 2017.
In VFL/AFL history, only 12 players have completed the feat from debut.
Marinoff, who will line up against Sydney at Unley Oval, can't help but compare the timeline to men's Lions player Hugh McCluggage, who reached 200 games this year when Brisbane defeated the Western Bulldogs in round 19.
"We got drafted in the same year (in 2016)," three-time premiership player Marinoff said of McCluggage's milestone.
"When you reflect on that and you have an understanding of just how many years we've been playing 10 or so games (in one season), it's pretty cool.
"To be the first alongside Ally to do it, it probably hasn't sunk in.
"What she's been able to do for the game is remarkable, she's an Indigenous woman and she's always held herself with great pride.
"She's someone that works hard as well, so to do it with someone similar, like for like, it seems fitting."
Two-time premiership player Anderson will mark the milestone when Craig Starcevich's Brisbane host Richmond at Brighton Homes Arena.
"I remember avoiding Craig in that first year, thinking I was going to get dropped every game," Anderson joked.
"I'm surprised that I've made it this far.
"To do it without any injuries or concussions or suspensions for nine years is a pretty good feat."
The milestone is yet another achievement to add to the star duo's glittering resumes.
Anderson boasts four-time club best-and-fairest awards, three All-Australian blazers and the 2022 (S7) league best-and-fairest gong to go with her premiership medals.
Reigning league champion Marinoff has seven All-Australian nods, is a three-time club champion and was the inaugural Rising Star winner in 2017.
A three-week suspension for forceful front-on contact in 2021 threatened to end Marinoff's streak, but the ban was overturned.
"I've played with a broken ankle, so I'm not quite sure what would stop me from playing the game that I love," the 27-year-old said.
With expansion to 14 rounds on the cards after this year's move to 12 games from 11 last year, Marinoff hopes the 100-milestone will soon become a regular occurrence in the women's competition.
Season expansion, according to a five-year collective bargaining agreement, is dependent on achieving an average attendance of 6000 fans and average broadcast viewers of 100,000.
"It kills me that at the end of the home-and-away season, you look at the ladder and there's only 12 games and there's 18 teams," Marinoff said.
"It just doesn't sit well with me that we don't play everyone once.
"I'd really love to see that happen in the next few years, so I'll be pushing for that."Â