From which it can be deduced that Ireland lost their opening match, badly, while Italy won.
That was the case with Ireland soundly beaten by France 36-14 in Paris while Italy defeated Scotland in Rome.
Ireland have handed Robert Baloucoune (wing) and Cormac Izuchukwu (back row) their tournament debuts.
Jack Conan comes in at No.8 while James Ryan, who made an impact off the bench in last week's defeat, starts at lock
Craig Casey replaces Jamison Gibson-Park at halfback in the other personnel change. In a positional switch captain Caelan Doris moves to openside flanker.
"There has been a positive reaction in training this week and we'll aim to keep on building into the weekend," Ireland coach Andy Farrell said.
For Italy Leonardo Marin moves from fullback to centre to replace Juan Ignacio Brex, who asked to be excused from the trip to Dublin for family reasons.
Lorenzo Pani comes off last weekend's replacement bench to take up the No.15 slot.
IRELAND
Osborne; Baloucoune, Ringrose, McCloskey, Lowe; S Prendergast, Casey; Loughman, Sheehan, Clarkson, McCarthy, Ryan, Izuchukwu, Doris (capt), Conan.
Replacements: Kelleher, O'Toole, Furlong, Edogbo, Beirne, Timoney, Gibson-Park, Crowley.
ITALY
Pani; Lynagh, Marin, Menoncello, Ioane; P Garbisi, Fusco; Cannone, Zuliani, Lamaro (capt), Zambonin, Cannone, Ferrari, Nicotera, Fischetti.
Replacements: Di Bartolomeo, Spagnolo, Hasa, Ruzza, Favretto, Odiase, A Garbisi, Odogwu.
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