His death was confirmed by NBC, the broadcast network that aired Friends for 10 years, on X, formerly known as Twitter.
"We are incredibly saddened by the too soon passing of Matthew Perry," it posted.
"He brought so much joy to hundreds of millions of people around the world with his pitch perfect comedic timing and wry wit. His legacy will live on through countless generations."
The Los Angeles Times and TMZ reported the American-Canadian performer was found dead in a hot tub or jacuzzi.
NBC News reported he was found dead of an apparent drowning at his Pacific Palisades home in Los Angeles.
We are incredibly saddened by the too soon passing of Matthew Perry. He brought so much joy to hundreds of millions of people around the world with his pitch perfect comedic timing and wry wit. His legacy will live on through countless generations. — NBC Entertainment (@nbc) pic.twitter.com/VcAlZ26NsoOctober 29, 2023
Ironically, Perry's last post on Instagram, on October 23, was a photo of him sitting by a pool or jacuzzi at night, captioned: "Oh, so warm water swirling around makes you feel good? I'm Mattman."
Perry was best known for his role as Chandler in the hugely successful Friends, which ran for 10 seasons from 1994 to 2004, co-starring Jennifer Aniston, Courteney Cox, David Schwimmer, Matt LeBlanc and Lisa Kudrow.
The series made celebrities of the six cast mates, playing a close-knit group of young adults who shared space in one another's apartments and met for coffee at Manhattan cafe Central Perk.
A major storyline involved a clandestine romance between Chandler and Monica, played by Cox, which the four other friends - Rachel, Joey, Phoebe and Ross - discovered one by one. The two characters eventually marry.
The group reunited 17 years after the series finale in a special that aired on HBO Max in 2021.
But none managed to rekindle the level of stardom and commercial success they garnered in what was for a time the most watched US. television program in prime time.
The hit NBC sitcom Friends shot Matthew Perry and his fellow cast mates to global stardom.
Hidden from public view during much of the original run was Perry's struggle with addiction to prescription drugs and alcohol, which he detailed in his 2022 memoir, Friends, Lovers and the Big Terrible Thing.
In a New York Times interview published in October 2022, Perry said he had been clean for 18 months, saying: "I've probably spent $9 million or something trying to get sober."
Perry recounted in his book that he had to be driven back to rehab right after shooting the episode of Chandler and Monica's wedding.
Following Friends, Perry starred in three short-lived network television ventures: Studio 60 on the Sunset Strip, Mr Sunshine and Go On.
He also logged guest appearances or recurring roles in other hit TV shows, including The West Wing, Ally McBeal, Scrubs and Beverly Hills, 90210. His film credits include Fools Rush In, The Whole Nine Yards, Almost Heroes and Three to Tango.
Perry received one Emmy nomination for his Friends role and two more for his role on The West Wing.
Matthew Perry's passing is shocking and saddening. I'll never forget the schoolyard games we used to play, and I know people around the world are never going to forget the joy he brought them. Thanks for all the laughs, Matthew. You were loved – and you will be missed.— Justin Trudeau (@JustinTrudeau) October 29, 2023
The Massachusetts-born actor grew up in Ottawa after his mother, a Canadian journalist who once served as press secretary to former prime minister Pierre Trudeau, divorced Perry's father and married a Canadian broadcast personality.
Trudeau's son and incumbent Canadian Prime Minister Justin Trudeau responded to his boyhood friend's "shocking and saddening" death.
"I'll never forget the schoolyard games we used to play, and I know people around the world are never going to forget the joy he brought them," Trudeau wrote on X.
As a youngster, Perry became a top-ranked junior tennis player before moving to LA to pursue acting and improvisational comedy.
with AP
