"It's clear to me that a majority of Republican primary voters want to give Donald Trump another chance," he said in a video posted on X, formerly known as Twitter.
New Hampshire's first-in-the-nation primary comes on Tuesday.
The ambitious big-state governor entered the 2024 presidential contest with major advantages in his quest to take on Trump, and early primary polls suggested DeSantis was in a strong position to do just that.
"Success is not final, failure is not fatal: it is the courage to continue that counts."— Ron DeSantis (@RonDeSantis) - Winston Churchill pic.twitter.com/ECoR8YeiMmJanuary 21, 2024
He and his allies amassed a political fortune well in excess of $US100 million ($A152 million), and he boasted a significant legislative record on issues important to many conservatives, like abortion and the teaching of race and gender issues in schools.
Such advantages did not survive the reality of presidential politics in 2024.
From a high-profile announcement that was plagued by technical glitches to constant upheavals to his staff and campaign strategy, DeSantis struggled to find his footing in the primary.
He lost the Iowa caucuses - which he had vowed to win - by 30 percentage points to Trump.
And now, DeSantis' political future is in question after suspending his presidential bid after just one voting contest.
The 45-year-old is term limited as Florida governor.
