A handful of Bulldogs players battled the virus last week including on game day for their defeat of St George Illawarra last Saturday.
Eight players and two staff members were isolated from training on Monday to manage their illnesses, but the full complement had returned by Thursday's captain's run.
"Everyone's good, everyone's back on deck," said coach Cameron Ciraldo.
"It was more precautionary at the start of the week, obviously it was just a light session ... so we started to keep the guys away from each other until after the day off."
The situation on Monday was so grim that SG Ball coach and former player Steve Turner filled in during training, though Ciraldo declined to join him.
"I was slow when I played, so I'm no faster now," Ciraldo joked.
News of a healthy squad will come as a relief for a Bulldogs team that needs to upset the second-placed Panthers to keep their realistic finals hopes alive.
The ninth-placed Bulldogs would remain mathematically in contention with a loss, but their finals dream would be over if South Sydney and North Queensland won later in the weekend.
"We're not talking about what's on the line in a big picture sense," Ciraldo said.
"We've got a very short-term focus, we want to stay present throughout that 80 minutes. If we can do that and get our game on, then we give ourselves an opportunity."
Working in their favour is the Bulldogs were the first team to beat Penrith this year, comprehensively outplaying the premiership favourites for a 32-16 win in April.
Halfback Lachlan Galvin starred that night as Canterbury made a fast start and exploited the Panthers' shaky left-edge defence.
"This next instalment will be (about) who can learn the most from that game," said Ciraldo, a former Penrith assistant coach.
"We've evolved as a team a lot since then. We've had to go through some tough times and we've gone through our last 12 weeks of performing quite well."
The game comes only three days after the Bulldogs signed important second-rower Jacob Preston to a long-term contract extension.
Ciraldo had never doubted the Bulldogs' ability to retain Preston, despite his management's public claims of being low-balled during negotiations.
"I told you so," Ciraldo said of the re-signing news.
"It's been awesome to watch Jacob's journey over the last four years.
"I'm really excited to have him around a lot longer."