The ChatGPT-maker is endorsing the Web of Biological Data Act, the AI-Ready Bio-Data Standards Act and the Scale Biology Act, the spokesperson said.
OpenAI is also backing a key provision of the FRONTIER Act that requires leading artificial intelligence companies to embed independent evaluators to assess the safety of their models, the spokesperson said.
Concerns about advanced AI have escalated, with heads of top US AI labs including OpenAI also calling for a slowdown in the pace of advanced AI development.
Last week, OpenAI said it was pushing for mandatory national AI safety requirements in the United States.
Separately, OpenAI is working with rivals Anthropic and Alphabet's Google DeepMind on AI safety, Bloomberg News reported, citing the ChatGPT maker's global policy chief Chris Lehane.
Global concerns about AI's existential risks have risen after the heads of America's leading AI labs came together in a show of unity over the weekend to call for a pause in the development of the technology.
Lehane said OpenAI had been in talks with Anthropic and Google for several weeks and did not believe the three AI firms needed an antitrust waiver to co-ordinate on safety issues, according to the report.
"It's better to try to work together to prioritise safety," Lehane said at a briefing in Washington, according to Bloomberg News.
Lehane said OpenAI would support any bipartisan legislation aimed at mitigating catastrophic AI risks, according to the report.
OpenAI, Alphabet and Anthropic did not immediately respond to Reuters requests for comment.
Reuters could not independently verify the report.